ncRNA name | ANRIL |
ncRNA Category | lncRNA |
ID | 100048912 |
Ensembl | ENSG00000240498 |
Synonyms | CDKN2B-AS1, CDKN2B-AS, CDKN2BAS, NCRNA00089, PCAT12, RP11-145E5.4, p15AS |
Disease name | retinoblastoma (RB) |
Species | Homo sapiens |
Tissues/Cell_line | RB cell lines HXO-RB44 and Y79 |
Methods | transfection, qRT-PCR, Western blot, CCK-8 assay, flow cytometry, transwell assay |
Expression pattern | up-regulated |
Functional description | ANRIL depletion could act to suppress retinoblastoma progression by activating the ATM-E2F1 signaling pathway. |
PubMed ID | 30355646 |
Year | 2018 |
Title | The silencing of long non-coding RNA ANRIL suppresses invasion, and promotes apoptosis of retinoblastoma cells through the ATM-E2F1 signaling pathway. |
Drug-related ncRNA | NO |
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